Smoking-associated fibrosis and pulmonary asbestosis
نویسندگان
چکیده
منابع مشابه
Smoking-associated fibrosis and pulmonary asbestosis
The diagnosis of pulmonary asbestosis is most often established based on clinical criteria and has both clinical and legal implications. Unfortunately, one of the confounding features in the diagnosis may be a history of cigarette abuse, which can produce interstitial opacities on chest imaging as well as diffusion defects on pulmonary function testing, criteria that are used in the diagnosis o...
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License. The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. Permissions beyond the scope of the License are administered by Dove Medical Press Limited. Information on how to request permission may be f...
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solely to the receptor, studies were undertaken utilizing fluoride ion (F-) and GMP-PNP (a synthetic guanyl nucleotide). Both of these reagents stimulate adenylate cyclase via a mechanism independent of the beta receptor. Again the addition of ThI to samples stimulated with either fluoride or GMP-PNP produce identical responses, 44 and 43 percent inhibition respectively. These results are in di...
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Idiopathic pulmonary fibrosis (IPF) is a disease of unknown etiology with considerable morbidity and mortality. Cigarette smoking is one of the most recognized risk factors for development of IPF. Furthermore, recent work suggests that smoking may have a detrimental effect on survival of patients with IPF. The mechanism by which smoking may contribute to the pathogenesis of IPF is largely unkno...
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The relationship between smoking and pulmonary fibrosis is under debate and intense investigation. The aim of this paper is to review the existing literature and identify further areas of research interest. Recently the negative influence of cigarette smoking on IPF outcome was highlighted, as non-smokers exhibit a better survival than ex-smokers and combined current- and ex-smokers. In patient...
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ژورنال
عنوان ژورنال: International Journal of Chronic Obstructive Pulmonary Disease
سال: 2014
ISSN: 1178-2005
DOI: 10.2147/copd.s74643